Tuesday, 15 June 2021

09:00 – 09:10

Remarks from ASIATOX President & Introduction to Keynote Speaker

09:10 – 09:50

Keynote. The Botanical Safety Consortium: A Public-Private Partnership to Enhance the Botanical Safety Toolkit

Connie Mitchell, Health & Environmental Sciences Institute, USA

Day 2 Subtheme: Emerging Issues in Toxicology

09:50 – 10:00

Symposium 4: Emerging Issues of Herbal Medicine Safety

Chairs: Nurşen Başaran, Hacettepe Uni., Turkey; Nan Mei, FDA, USA

Symposium 5: When & How We Can Stop Using Animals in Toxicology

Chair: Emanuela Corsini, Uni. of Milan, Italy;

Thomas Hartung, CAAT, USA

Workshop 2: Chemical Stewardship: Global Regulations and Beyond Compliance in Meeting Sustainable Performance of Energy Industry

Chair: Hazlina Yon, DOSH, Malaysia

10:00 – 10:30

Unpredictable Adverse Effects of Herbal Products

Nurşen Başaran, Hacettepe Uni., Turkey

Applicability Domains and Future of Non-animal Tests

Nicole Kleinstreuer, NIH, USA

Regulatory Expectations for Sustainable Chemicals Management in Developing Countries

Hazlina Yon, DOSH, Malaysia

10:30 – 11:00

Complementary and Alternative Medicines: Malaysia Scenario

Seetha Ramasamy, NPRA

The View of the Chinese Centre for Alternative Research and Evaluation

Shujun Cheng, Shanghai Jiaotong Uni., China

Managing Trade Barrier through Application of Globally Harmonized System (GHS) to Petroleum Substances

Jessica Ryman-Rasmussen, API

11:00 – 11:20


11:20 – 11:50

Registration of Herbal Drugs in EMA

Heidi Foth, Martin Luther Uni., Germany

The AFSA Collaboration: Implementing Animal-Free Safety Assessment of Cosmetics Globally

Catherine Willett, Human Soc International Europe

UNITAR’s Perspective on the Emerging Beyond 2020 Framework and What it Means for the GHS and PRTRS

Oliver Wootton, UN Inst. Training & Research; Servet Goren, Cefic

11:50 – 12:20

Quantitative Analysis of Toxicity Data of Herbal Products

Nan Mei, FDA, USA

The Way Forward: The Experience at CAAT

Thomas Hartung, CAAT, US

Managing Environmental Health Risks in the Oil & Gas Industry

Nor Rahmah Nor Hashim, PETRONAS

12:20 – 12:50

Herbal Products: Regulation and Safety Testing in Thailand.

Rawiwan Maniratanachote, NSTDA, Thailand

Immunotoxicology: A History of a Success

Emanuela Corsini, Uni. of Milan, Italy

Question and Answer Session

12:50 – 13:10

Question and Answer Session

13:10 – 14:10


14:10 – 14:20

Oral Session 3: Herbal/Natural Product Toxicology

Chair: Salfarina Ramli, UiTM

Oral Session 4: Genotoxicity

Chair: Mogana Das Murtey, Uni. Sains Malaysia, Malaysia

Oral Session 5: Mechanistic Toxicology

Chair: A’edah Abu Bakar, PETRONAS, Malaysia

14:20 – 14:50

Ochratoxin A and Antioxidant Activities of Roasted Coffee Beans in Phnom Penh, Cambodia (OS3-O01)

Oeung Sokunvary, Khon Kean Uni., Thailand

Pharmacological Activation of Autophagy Restores Cellular Homeostasis in UVB-Induced Genotoxic Stress Response in Skin (OS6-O02)

Sheikh Umar Ahmad, Indian Institute of Integrative Medicine, India

Comprehensive Histone, DNA Methylation and mRNA Expression Analysis of Murine Liver Repeatedly Exposed to Chemicals (OS5-O02)

Jun Kanno, NIEHS, Japan

14:50 – 15:20

Antioxidant Activities & Anti-inflammation of Coelonin from Dendrobium scabrilingue (OS3-O05)

Hasseri Halim, Uni. Technology MARA, Malaysia

The Presence of Genotoxic and Carcinogenicity Phytochemicals in Medicinal Plants Based on the Malaysian Herbal Monograph (OS3-O02)

Nur Azra M Pauzi, Uni. Putra Malaysia, Malaysia

Fibroblast Growth Factor Receptor 4 as a Potential Druggable Target for Triple Negative Breast Cancer (OS5-O03)

Koh Yong Qin, National Uni., Singapore, Singapore

15:20 – 15:40


15:40 – 16:10

Fish Acute Toxicity Testing of Litsea Garciae Methanolic Extract in Adult Zebrafish (OS3-O03)

Siti Zaleha Raduan, Int. Islamic Uni., Malaysia, Malaysia

Role of Nrf2/Nqo1 Pathway in Mediated Arsenite-Induced Malignant Transformation (OS5-O01)

Yan An, Soochow Uni., China

Cerium Oxide Nanoparticles a Potential Therapy for Hepatic Fibrosis Symptoms (OS8-P02)

Adrian Boey, National Uni. of Singapore, Singapore

16:10 – 16:40

Toxicity Studies of Supercritical Fluid Extract of Local Ziziphus Mauritiana (Bidara) Fruit (OS3-O04)

Arnida Hani Teh, Uni., Kebangsaan Malaysia, Malaysia

Overview of Genotoxicity Field in Malaysian Environment (OS6-O01)

Mogana Das Murtey, Uni. Sains Malaysia, Malaysia

Reduction of Arsenic Toxicity Through Nrf2 Activation Mediated by (2)-2-Alkenals in Coriandrum Sativum L. Leaf Extract (OS5-P01)

Hanako Aoki, Uni. of Tsukuba, Japan

16:40 – 17:00

Question and Answer Session